No maximum tolerated dose, or MTD, was reached. Maintain our culture of innovation, execution and efficiency. These formatting challenges may restrict broad applicability of this technology. It is estimated that as many as 43,000 people worldwide die from mesothelioma each year. It can also form in soft tissues in the lung or abdomen. Gastric AdenocarcinomaGastric cancer is the second most common cancer worldwide. INBRX-106 was found to mediate similar co-stimulation of CD4 and CD8 T-cells. The image below illustrates the unique structure of INBRX-105. However, INBRX-105 does not interact with either mouse PD-L1 or 4-1BB. Exploratory endpoints include NE activity and its biomarkers. We are currently in discussions with Transcenta regarding these matters. The March TSA 35Table of Contentshad a six month term and expired in September 2018. We were reimbursed $0.4 million in October 2018 for the October TSA. Some nonclinical testing may continue even after the IND is submitted. PDUFA also imposes an annual program fee for prescription biological or drug products. The BPCIA is complex and only beginning to be interpreted and implemented by the FDA. Investing in our common stock involves a high degree of risk. As of December 31, 2020, we had an accumulated deficit of $145.4 million. In the event of any such decision, we would be unable to advance such program ourselves. Ultimately, Chiesi may not exercise its option pursuant to the Chiesi Agreement. It is unknown how long these disruptions could continue, were they to occur. Litigation may be necessary to defend against these claims. Our business may be adversely affected as a result of computer system failures. This could lower the price that we receive for any approved product.