Our vision is to provide life-long cures to patients suffering from serious diseases. In some cases, a new product candidate may only require changing the guide RNA. CRISPR proteins incorporate a programmable component called a guide RNA. By changing the deaminase, we can control which base is edited (e.g., C or A). We believe base editors may be an ideal tool for repairing point mutations. & Levels of editing were sustained after long-term hematopoietic engraftment. We have developed several proprietary LNP formulations. These protocols included several shifts working over a seven-day-week protocol. We refer to this license agreement as the Editas License Agreement. In addition, on May 30, 2018, the Right to Try Act was signed into law. The CCPA contains significant penalties for companies that violate its requirements. This also applies to biosimilars. Thus, obtaining and maintaining reimbursement status is time-consuming and costly. Other reform efforts affect pricing or payment for drug products.& & Information on our website is not incorporated by reference herein. As of December 31, 2020, we had an accumulated deficit of $397.6 million. The net losses we incur may fluctuate significantly from quarter to quarter. We were founded and commenced operations in January 2017. Our current technology cannot edit within the mitochondria. We are very early in our development efforts. Currently, all of our product candidates are in preclinical development or in discovery. In certain of our programs, we plan to use LNPs to deliver our base editors. No gene editing therapeutic product has been approved in the United States or in Europe. A failure of one or more clinical trials can occur at any stage of testing. We cannot predict the success of any collaboration that we enter into. The scope of patent protection outside of the United States is also uncertain. The patent was revoked due to loss of priority. Violation of the FCPA can result in significant civil and criminal penalties. We do not expect to pay any dividends for the foreseeable future. In addition, our remediation efforts may not be 91 & successful.